The Synthetic Organic Chemistry Core Laboratory offers services in the areas of synthesis and development of new methods and protocols for the synthesis of modified oligonucleotides, modified peptides, bioconjugates, small molecules and novel research tools for biomedical and environmental health research.  Nucleosides, representing known DNA damage are a specialty of the SOCCL and can be synthesized and subsequently converted into phosphoramidites for incorporation into synthetic DNA sequences site specifically during synthesis or via post-synthesis methods. Protocols for purifying and analyzing for all products are also developed as needed in the SOCCL. Synthetic organic services continue expansion to accommodate a growing need for synthesis and purification of modified peptides in collaboration with UTMB’s Biomolecular Resource Facility, bioconjugates, small organic molecules and novel research tools of interest to biomedical and environmental health researchers at UTMB.